Terms
to Know - By First Letter |
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ABO
- Blood Type - Proteins present in our blood cells
(and most other cells) which are inherited from our parents and may present
a barrier to receiving blood transfusions or organ transplantation.
Your ABO - Blood Type is taken into consideration when you are waiting
for a donor. (top)
ABO Testing - Blood tests that classify human blood
into one of four groups: O, A, B, or AB. (top)
ac - Before meals. (top)
Acute Rejection - The body's attempt to destroy the
transplanted organ. Acute rejection usually occurs in the first year
after transplant. (top)
ad lib - To the amount desired or as frequently as
desired. (top)
ADA -
Americans with Disabilities Act of 1990. (top)
Adverse Reaction - An unintended side effect from a
drug. (top)
Advocacy Organization - A group that helps someone
get what they need or want, promotes a certain point of view, or
pleads the case of another. (top)
AIDS - Acquired Immune Deficiency Syndrome (top)
Albumin -
Albumin is a protein made by the liver that helps maintain fluid
balance in the body. (top)
Allocation - The process of determining how organs
are distributed. Allocation includes the system of policies and guidelines
that are followed to ensure that organs and tissues are distributed
fairly to those waiting for them. (top)
Allograft - An organ or tissue transplanted from one
individual to another of the same species i.e., human to human.
Example: a transplanted kidney.(top)
Anemia - A decreased amount of circulating red blood
cells in the body. Anemia may result from blood loss, destruction
of red blood cells or a decrease in the production of red blood
cells. The hemoglobin level (hgb) is decreased in patients with anemia. (top)
Antibody -
A protein substance made by the human body in response to a foreign
substance, for example, a previous transplant, blood transfusion,
virus or pregnancy. Because antibodies attack the transplanted organ,
transplant patients must take drugs to prevent organ rejection. (top)
Antigen - A foreign substance, such as a transplanted organ,
that triggers an immune system response. This response may be the production of
antibodies, which try to destroy the antigen. (top)
Anti-rejection
Drugs (Immunosuppressive Drugs) - Medicines developed to
suppress the immune response so that the body will accept, rather
than reject, a transplanted organ or tissue. These medicines are
also called immunosuppressants. (top)
apmt, appt - Appointment (top)
Arteriogram - An arteriogram is a radiologic study
(x-ray) or picture of the arteries in an organ system that is visualized
through a special dye that is infused in the blood stream. (top)
Ascites - An abnormal accumulation of fluid in the
abdomen. (top)
B Cells -
B cells are a type of lymphocyte or white blood cell, that
develop in the spleen and are responsible for the body's
immunity. B cells produce antibodies which help fight infection and foreign
substances. (top)
Beneficiary - The person or other party designated to receive life insurance policy proceeds. (top)
Benefits - Services that are paid for by an insurance policy. (top)
bid - 2 times per day. (top)
Bile -
Fluid made by hepatocytes, the liver cells, that is secreted into the bile
ducts and then into the small intestine to help absorb fats. (top)
Bile Duct -
A vessel in the liver that carries bile from the liver cells to the common
bile duct. The common bile duct then carries bile into the intestine. (top)
Bilirubin -
A substance made from the break down of hemoglobin. Hemoglobin
is a substance in red blood cells that carries oxygen to body tissues. Red
blood cells are trapped and destroyed in the spleen as they wear out. When
these cells are destroyed, bilirubin is released into the blood (unconjugated
bilirubin). The liver then processes this type of bilirubin, combines
it with another substance and excretes the bilirubin (called
conjugated bilirubin) through bile. Bile flows from the individual
liver cells, through the bile ducts, and into the intestine
where it leaves the body in the feces. The characteristic
brown color of feces is due to bile. Patients with liver
disease often have clay-colored or tan feces since the liver may
not be producing bile due to missing or blocked bile ducts.
(An elevated bilirubin level may also be a sign of liver rejection.) (top)
Biopsy -
A biopsy is a procedure that provides a small amount of tissue
from an organ, tumor, bone, or other body tissue to find
out more information about that organ or tissue. A core needle biopsy is
usually performed to examine liver tissue. A tiny cylinder of tissue, showing
liver cells and how they are arranged, is removed through puncture with
this needle. This tissue is examined under the microscope by a
pathologist to determine the cause of liver disease, or
to look for any evidence of rejection or infection. (top)
Blood Urea Nitrogen (BUN) - A test that indicates kidney function.
The BUN is a product of protein breakdown, or waste product,
normally excreted by the kidney. (top)
Blood Vessels -
The veins, arteries and capillaries through which blood flows. Blood vessels
can be donated and transplanted. (top)
BM - Bowel movement (top)
BP - Blood pressure (top)
BR - Bathroom or bed rest (top)
Brain
Death - When the brain
has permanently stopped working, as determined by the physician.
Artificial support systems may maintain functions such
as heartbeat and respiration for a few days, but not permanently. (top)
BS - Blood sugar (top)
BUN - Blood urea nitrogen (top)
C
C&S - Culture and sensitivity (top)
Cadaver - A dead body. (top)
Cadaver Donor
- Someone who has died and before death agreed to donate his or her organs. (top)
Cadaveric - Refers to things about or relating
to a dead body. (top)
Calcium -
A mineral measured in the blood that is required for bone
growth and for blood clotting. It is also needed for the
heart and nerves to function. (top)
Cardiac - Having to do with the heart. (top)
CAT - Computerized Axial Tomography (CAT
scan) (top)
Catheter -
A flexible tube that enters or exits the body. Catheters
may be used to drain body fluids (a Foley catheter drains
urine) or to administer fluids or medications through a
vein (a Broviac catheter). (top)
CBC - complete blood count (top)
CCU - Coronary or Cardiac Care Unit (top)
CHAMPUS - Civilian Health and Medical Program
of the Uniformed Services, now known as Tricare (top)
Charitable Organization - A group that does
not charge a fee for its services. (top)
Chimerism -
The existence of more than one genetic background within
one person. Transplant recipients show chimerism through
genetic markers since they have cells from the donor organ
in their bodies. (top)
Cholangitis -
A bacterial infection in the bile ducts of the liver. Cholangitis
can occur if bile flow is obstructed due to scarring of
the duct or an obstruction in the duct. It can also occur
in patients who had bile duct reconstruction or the Kasai
procedure when bacteria from the intestine can invade the
liver. Symptoms of cholangitis may include fever, an elevated
bilirubin level, jaundice and low blood pressure. Antibiotics
are used to treat cholangitis. Patients with recurrent
cholangitis may be prescribed a preventative dose of antibiotic
daily. Treatment of the obstruction through surgery or
transplantation will ultimately resolve cholangitis. (top)
Cholestasis -
An accumulation of bile in the liver. This can be caused
by medications, an injury to the liver, total parenteral
nutrition (TPN) or gallstones and may resolve over time
or when medications or TPN are discontinued. Cholestasis
may also occur as a symptom of many liver diseases. (top)
Cholangiogram - A test that examines the
bile ducts in the liver for any leaks or blockages. A dye
is injected into the bile ducts and then the liver is examined
through an x-ray. (top)
Chronic -
Having a disease for a long period of time. Chronic disease
may worsen slowly over time. (top)
Chronic Rejection - Slow failure of the transplanted
organ. (top)
Cirrhosis -
Cirrhosis occurs when something destroys the liver cells
causing the cells to die. When many cells die, there is
scarring throughout the liver. A cirrhotic liver becomes
very firm, unlike its normal spongy texture, and can be
shrunken in size or enlarged. (top)
cm - centimeter (top)
CMS - Centers for Medicare and Medicaid Services
(previously known as the Health Care Financing Administration
or HCFA) (top)
Coagulation -
The process of blood clotting. A variety of factors are
necessary for the blood to have a normal clotting ability.
Clotting ability is assessed by several blood tests including
the prothrombin time (PT), partial thromboplastin time
(PTT) and platelet count. An abnormal clotting time is
often see in patients with liver disease. (top)
Coagulopathy - Decreased ability of the blood
to clot which increases the risk of bleeding, particularly
with surgery or any invasive procedures such as biopsies. (top)
COBRA - Consolidated Omnibus Budget Reconciliation
Act of 1985 (top)
Co-insurance - A percentage of money you
must pay toward a service your insurance will cover. (top)
Cold Ischemia
Time - The time
an organ is without blood circulation -- from the time
of removal of the organ from the donor to the time the
organ is transplanted into the recipient. (top)
Complete Blood
Count (CBC) - A blood test
that measures many parts of your blood including
the hemoglobin (hgb), hematocrit (hct), platelets (plt)
and many types of white blood cells (WBC). (top)
Compliance -
The act of following orders, adhering to rules and policies. Cooperation
with the instructions, prescriptions and directions from
your health care team; taking responsibility for your
own health by following the advice of your doctors, nurses,
and therapists.
(top)
Co-payment
(co-pay) - A flat fee that a
person pays for healthcare services in addition to what
the insurance company pays. (top)
Corticosteroid - A hormone produced by
the body but given as a synthetic (manufactured) medicine
to suppress your body's normal reaction (immune response)
to infection and foreign tissue, such as a transplanted
organ. Prednisone is an example of a synthetic hormone.
(top)
Coverage Date - The day your insurance
benefits begin.
(top)
Covered Benefit - A service that an insurance
company will provide payment toward.
(top)
Covered Service -
See Covered
Benefit. (top)
CPR - Cardiopulmonary resuscitation (top)
Cr - Creatinine (top)
Creatinine - The creatinine level is an
indication of kidney function. It is a waste product
produced by the muscles and released into the blood stream.
Creatinine levels may be increased with kidney disease.
Abnormal creatinine levels are also seen in patients
with kidney dysfunction caused by liver disease or medications. (top)
Criteria (Medical
Criteria) - A set of standards
or conditions that must be met. (top)
Critical Care
Unit - See Intensive
Care Unit. (top)
Crossmatch - A blood test for patient antibodies
against donor antigens. A positive crossmatch shows that
the donor and patient do not match. A negative crossmatch
means there is no reaction between donor and patient and
that the transplant may proceed. (top)
Ctr - Center (Medical Center) (top)
CT Scan -
Computer Tomography Scan - A noninvasive
radiologic study that shows a detailed cross-section of organ
and tissue structure. (top)
Cyclosporine - A drug used to prevent rejection
of the transplanted organ by suppressing, or shutting down,
the body's defense system (immune response). (top)
Cytomegalovirus
- CMV - A virus commonly seen
following transplantation that can cause an infection in
the gastrointestinal tract, blood, liver, lungs and/or
eyes. CMV is a type of herpes virus. (top)
DC, D/C - Discharge, discontinue (top)
DDS - Doctor of dental surgery (top)
Deceased Donor - A person who has been declared dead and whose
family has offered one or more organs or tissues to be used
for transplantation. The deceased donor contrasts with the
living donor, someone who has agreed to donate a kidney or
part of an organ while still alive. (top)
Deductible -
A fixed amount of money you must pay for covered healthcare expenses before
the insurance company starts to pay. This is usually a yearly amount of
$250, $500, $1000, or more. (top)
Delayed Function - A condition in which the transplanted organ
does not work well right after the transplant. (top)
Department of Health and Human
Services (HHS) - The department
of the Federal Government responsible for health-related
programs and issues, including overseeing the OPTN and SRTR
contracts and developing organ, tissue and bone marrow donation
programs. (top)
Dependents - Those persons who also receive insurance benefits
on your policy, for example, a spouse and/or children. (top)
Depilatory - A cream or spray put on the skin to dissolve
and remove excess hair. (top)
Diabetes -
A disease originating in the pancreas related to insulin production that
causes high levels of glucose (sugar) in the blood. (top)
Dialysis - A procedure to remove waste products from the blood
in patients with kidney disease. Patients with severe liver
disease who develop kidney dysfunction may require dialysis
until normal kidney function returns. (top)
Diastolic -
This is the "bottom number" of blood pressure
measurement when the heart muscle is at rest, expanding and
filling with blood. (top)
Diastolic Blood Pressure - The bottom number in your blood
pressure (80 in a blood pressure of 120/80), which indicates
the pressure in the arteries when the heart is at rest. (top)
Disability (Disabled) - A considerable limitation in major
life activity that cannot be helped with the use of a corrective
device or medication. A disabled person is someone who is
unable to perform the necessary functions of a job with or
without a reasonable modification. (top)
Disability Determination Service - A state agency that reviews
your eligibility for vocational rehabilitation. (top)
Disability Insurance -
A type of insurance that provides you with an income if illness
or injury prevents you from being able to work for an extended period of
time. (top)
Diuretic - A medicine that helps remove excess fluid from
the body tissue by causing the body to excrete sodium. Furosemide
(Lasix®) and spironolactone (Aldactone®) are diuretics . These
medications will increase urine output. (top)
DO - Doctor of Osteopathy (top)
Donor - An individual who donates part or all of an organ
to one in need of a transplant. (top)
Donor Card - A document that indicates your wish to be an
organ donor. (top)
Donor Pool - A group of people eligible to donate an organ. (top)
Durable
Power of Attorney - A document in which individuals may designate
someone to make medical decisions for them when they are
unable to speak for themselves. (top)
Dx - diagnosis (top)
ECG, EKG - Electrocardiogram (top)
ED - Emergency Department (top)
Edema -
Swelling of tissue, particularly in the face, hands, legs and ankles. (top)
EEG - Electroencephalogram (top)
EEOC - Equal Employment Opportunity Commission (top)
Electrocardiogram (EKG/ECG) - A noninvasive test that
records the electrical activity of the heart. (top)
Electrolytes -
The dissolved form of a mineral found in the blood that helps maintain
bodily functions and fluid balance. Sodium, potassium, chloride,
magnesium, calcium, and phosphorus and some of the electrolytes found
in your body. (top)
Encephalopathy - Confusion or an altered mental status.
Encephalopathy may be seen in patients with end-stage liver disease.
Due to liver dysfunction ammonia cannot be metabolized by the liver.
Ammonia builds up in the brain and interferes with oxygen getting
to the tissue, causing confusion and tiredness. Medications such
as lactulose, and a low protein diet can help decrease the ammonia
level so that the patient does not develop encephalopathy. (top)
End Stage Organ Disease - A disease that leads to permanent
failure of an organ. (top)
End Stage Renal Disease
(ESRD)/Chronic Kidney Failure - End-Stage Renal Disease/chronic
kidney failure. A condition in which the kidneys no longer function
and for which patients need dialysis or a transplant. (top)
ENT - Ears, nose, throat (top)
ER - Emergency Room (top)
ESRD - End-stage renal disease (top)
Enzyme - A protein made in the body that is capable
of changing a substance from one form to another. The ALT and AST
are enzymes found in liver cells.
(top)
ERCP - Endoscopic Retrograde
Cholangiopancreatogram - A test that examines the drainage system or ducts of the gall bladder,
pancreas and liver (the biliary tree). (top)
Evidence of Insurability -
Proof that you are healthy enough for a particular insurance company to insure
you. (top)
Ex - Examination or exercise (top)
Exclusion -
Medical services that are not paid for by an insurance policy. (top)
Experimental - New treatments, procedures or drugs that are being
tested. (top)
F
FDA - U.S. Food and Drug Administration (top)
Federally Mandated - Required by Federal law. (top)
Fibrosis - The presence of fibrous tissue in the liver
that causes scarring and liver dysfunction. Fibrosis develops into
cirrhosis. (top)
Foreign Body - An entity that enters the body that
is not supposed to be there, such as a germ, a piece of glass, a
splinter or a transplanted organ or tissue. Your immune system normally attacks
or tries to reject a foreign body to prevent further injury. (top)
Foundation - An institution that provides funds for
causes, issues, groups, people, etc. (top)
Full Blood Count (FBC) - A
blood test that measures many parts of your blood count including the
hemoglobin (hgb), hematocrit (hct), platelets (plt) and many types
of white blood cells (WBC). (top)
Fulminant - Happening very quickly and with intensity,
for example, fulminant liver failure or fulminant infection. (top)
Fulminant Liver Failure - A severe from of liver disease that
starts, then progresses very rapidly. (top)
Fungal Disease - An infection. Examples
of fungal infections include candida, aspergillus, and histoplasmosis,
which tend to be systemic infections. (top)
FUO - Fever of unknown origin (top)
Gall Bladder - A small sac-like object attached to the liver
that stores bile. (top)
Gastroenterologist -
An internal medicine physician who specializes in diagnosing and treating
diseases of the intestinal tracts and its associated organs such as the liver,
bile ducts and pancreas. (top)
Gastroesophageal Varices -
A disease which causes enlarged veins of the esophagus and stomach due to scarring in the
liver that obstructs the normal flow of blood through the liver. (top)
Gender -
The particular sex of an individual; male or female.(top)
Genetic - Referring to heredity, birth or origin. (top)
Genetic Matching - See tissue typing. (top)
GI - Gastro-intestinal (top)
Gingival Hypertrophy - Enlargement of the gums. It can be controlled
by good oral hygiene and regular dental checkups. (top)
Glomerular Filtration Rate (GFR) - A measurement of kidney function
used to determine the severity of kidney disease. (top)
Glucose -
A type of sugar in the blood that supplies energy to the cell. Glucose
levels may vary with diet, medications, stress and organ dysfunction. (top)
GP - General practitioner (top)
Graft -
An organ or tissue that is taken from one person and placed into
another (transplantation). A graft between humans or the same species
with different genetic material is called an allograft. (top)
Graft Survival Rate - The percentage of patients who have functioning
transplanted organs (grafts) at a certain point in time. The data
is usually measured in one, three and five year time periods. (top)
Grant - An amount of money given as a gift, usually for a specific
use. (top)
Group Health Plan - See Group Insurance. (top)
Group Insurance -
Typically offered through employers, although unions professional associations
and other organizations also offer group insurance. Most, of not all, of the
premium is paid by the employer. (top)
gtt, gtts - Drop (top)
HCFA - See CMS (top)
hct - Hematocrit (top)
Health Maintenance Organization
(HMO) - An
insurance plan where you or your employer pay a fixed monthly fee
for services, regardless of the level of care. You must usually
see your primary care physician and then be referred to a specialist. (top)
Hematocrit (HCT)
- A measurement of the amount of red blood cells in the blood. (top)
Hematoma -
A bruise; Swelling caused by the accumulation of blood tissue. (top)
Hemodialysis - A treatment for kidney failure whereby
the patient's blood is passed through a machine to remove excess
fluid and wastes. The procedure usually takes about three to four hours
per session and is usually done about three times per week. (top)
Hemoglobin (HGB) -
A substance in red blood cells that gives blood its characteristic
red color and contains iron and protein. Hemoglobin carries oxygen
from the lungs to the tissues and carbon dioxide from the tissues
to the lungs. (top)
Hemorrhage - A rapid loss of a large amount of blood;
excessive bleeding. (top)
Hepatic - A term that refers to the liver or having
to do with the liver. (top)
Hepatic Artery -
The blood vessel that carries oxygenated blood to the liver from
the heart. (top)
Hepatic Vein -
The blood vessel that carries deoxygenated blood from the liver to
the heart. (top)
Hepatitis - An inflammation of the liver, usually caused
by infection. (top)
Hepatologist - A doctor who specializes
in caring for patients with liver disease. (top)
Hepatomegaly -
A term that describes an enlarged liver. (top)
Herpes - A family of viruses that causes infection
in humans. (top)
hgb - Hemoglobin (top)
HHS - U.S. Department of Health and Human Services (top)
High Blood Pressure (Hypertension) -High blood pressure
occurs when the force of the blood pushing against the walls of the
blood vessels is higher than normal because the blood vessels have
either become less able to stretch or have gotten smaller. High blood
pressure causes the heart to pump harder to move blood through the
body. High blood pressure can cause kidney failure and heart disease
if not treated. (top)
HIPAA - Health Insurance Portability and Accountability
Act (top)
Hirsutism -
Excessive hair growth. Hirsutism is a common side effect of cyclosporine(medication). (top)
Histology -
The study of living tissue. The histology of a liver disease, for
example, would be determined by examining a piece of liver tissue
from a biopsy under a microscope. (top)
Histocompatibility (HLA
System) - The examination
of human leukocyte antigens (HLA) in a patient, often referred
to as
"tissue typing" or "genetic matching." Tissue
typing is routinely performed for all donors and recipients to help match the donor with the most
suitable recipients to help decrease the likelihood of rejection
of the transplanted organ. (top)
Human Leukocyte
Antigens - Markers found on cells in the body that
distinguish each individual as unique. Human leukocyte antigens (HLA)
are inherited from one's parents. In donor-recipient matching, HLA
determines whether an organ from one individual will be accepted
by another. (top)
Human Leukocyte Antigens (HLA) System - There are three major genetically controlled
groups: HLA-A, HLA-B, and HLA-DR. In transplantation, the HLA tissue
types of the donor and recipient are important in deciding whether
the transplant will be accepted or rejected. Genetic matching is
generally performed on kidneys and pancreata only. (top)
HMO - Health maintenance organization that provices insurance. (top)
HRSA - Health Resources and Services Administration (top)
hs - hour of sleep (top)
Human Immunodeficiency
Virus (HIV) -
A virus that destroys cells in the immune system, resulting in
the eventual inability of the body to fight off infections, toxins,
poisons, or diseases. HIV causes AIDS (Acquired Immunodeficiency
Syndrome). (top)
Human Leukocyte Antigens
(HLA) - Molecules
found on cells in the body that characterize each person as unique.
These antigens are inherited from your parents. In donor-recipient
matching, HLA determines whether or not someone will accept an
organ from a donor. (top)
Hyperlipidemia -
A high level of fats (triglycerides or cholesterol) in the blood.
This can be caused by diet, genetic disorders or medications. (top)
Hypertension - High blood pressure. (top)
ICU - Intensive Care Unit (top)
IM - intramuscular (injection) (top)
Immune Response - The body's natural defense against
foreign objects or organisms such as bacteria, viruses or transplanted
organs or tissue. (top)
Immune
System - A number of defenses, both cells and
substances (such as antibodies) in your body which are designed to protect you
from infections, but can also recognize and attack transplanted organs. (top)
Immunity -
The ability of the body to resist a specific disease. (top)
Immunization - Providing the body with protection from
certain diseases through vaccinations. (top)
Immunosuppressant - A drug used following transplantation
to prevent rejection of the transplanted organ by suppressing the
body's defense system. Drugs commonly used include tacromilus (Prograf,
FK506), cyclosporine (Sandimmune, Neoral, Gengraf), prednisone (Deltasone,
generics), azathioprine (Imuran), basiliximab (Simulect), daclizumab
(Zenapax), mycophenolate mofetil (CellCept), sirolimus (Rapamune,
Rapamycin), and antithymocyte globulin (ATGAM, Thymoglobulin). (top)
Immunosuppressed - Describes the immune system of a
transplant recipient which is weakened or inhibited by certain medications.
Specific medications (such as cyclosporine, tacrolimus, and prednisone)
are used to lower the ability of the immune system to attack foreign
cells (the transplanted tissue). Immunosuppression will help decrease
the body's ability to reject the transplanted organ. (top)
Immunosuppression - The artificial suppression of the
immune response, usually through drugs, so that the body will not
reject a transplanted organ or tissue. (top)
Immunosuppressive -
Relating to the weakening or reducing of your immune system's responses
to foreign material Immunosuppressive drugs reduce your immune system's
ability to reject a transplanted organ. (top)
Infection -
Organisms such as bacteria, fungi and viruses that invade the body
and reproduce causing a variety of symptoms. (top)
Inflammation - The swelling, heat and redness your
body produces when it has an injury or infection. (top)
Informed
Consent - A process of reaching an agreement
based on a full understanding of what will take place. Informed consent
has components of information sharing, understanding
and freely make a choice. (top)
Inpatient Treatment -
Treatment in the hospital involving at least one overnight stay. (top)
Insulin -
A hormone secreted in the pancreas by the Islets of Langerhans that
regulates sugar metabolism. Insulin helps the body use sugar and
other carbohydrates. As insulin is released in the body, the blood
glucose level decreases. (top)
Insurance Benefits - Service paid for by an insurance
company. (top)
Intensive Care Unit (ICU) -
A unit in the hospital that has highly technical and sophisticated
monitoring devices and equipment for seriously ill patients. The
staff is specially trained to take care of these patients who are
often critically ill or recovering from surgery. (top)
Intravenous (IV) - Within the blood stream - Fluids and
medications may be given through your veins as well as by mouth. (top)
Investigational - A drug or procedure that is in a
research phase and has not yet been approved for patient use by the
Federal Drug Administration (FDA). Insurance companies normally do
not pay for investigational drugs or procedures. (top)
IV - Intranvenous (top)
IVP - intranvenous pyelogram an x-ray of urinary structures
with dye. (top)
Jaundice - Term used to describe a yellow appearance
of the skin and eyes commonly seen in patients with liver disease.
Jaundice results from an increased amount of bilirubin in the body. (top)
K - Potassium (top)
kg - kilogram (1 kg = 2.2 lbs) (top)
Kidneys - A pair of organs that remove wastes from your body through
the production of urine. The blood in your body passes through the
kidneys about 20 times every hour. (top)
L - liter (top)
lb - pound (top)
Legislation - A law or group of laws proposed or enacted
that have the force or authority of a government or other organization. (top)
Leukocyte - A white blood cell. (top)
Liver Function Tests (LFTs) - Blood tests used to determine how
well the liver is functioning. These include the ALT, AST, GGTP,
bilirubin and alkaline phosphatase. (top)
LifeCenter (formerly OVLC) - The organ procurrement agency here in Cincinnati
and the surrounding area that provides the specially trained personnel
who handle the organ donation process. (top)
Lifetime Cap - See Lifetime
Maximum. (top)
Lifetime Maximum -
The total amount of money your insurance company will pay out for
your covered expenses during your lifetime. Typical amounts are $150,000,
up to $5,000,000. Once you have reached your lifetime maximum, you
will no longer have insurance benefits. It is very important for
you to know how your insurance dollars are being spent. (top)
Liver - A large glandular organ attached to your digestive
tract by the bile duct, responsible for multiple important metabolic
functions. (top)
Liver Transplant - Surgical treatment for individuals
with end stage liver disease. (top)
Living Related Donor (LRD) -
An individual who is a relative of the recipient who undergoes an
operation to remove a part of his/her liver so it can be donated
to the patient. (top)
Living Unrelated Donor -
A person who is not related by blood who donates a kidney or part
of a lung, liver or pancreas to another person, such as a husband
who donates to a wife. (top)
LPN - Licensed practical nurse (top)
Lymphocytes - Cells produced by the lymph glands that
are responsible for immunity. They defend the body against infection
and foreign substances by producing antibodies and other substances. (top)
Magnesium - A mineral required for normal bodily function.
Magnesium is involved in nerve, skeletal muscle, heart and cell
function. It is also involved in blood clotting and the breakdown
of carbohydrates and proteins. (top)
Mail-Order Pharmacy -
A pharmacy that provides medicines and medical supplies via the mail. (top)
Managed Care - A term used to describe insurance programs.
Health maintenance organization (HMOs), preferred provider organizations
(PPOs) and point-of-service (POS) plans and utilization review are
all forms of managed care. (top)
Match - The degree of compatibility, or likeness, between
the donor and the recipient. (top)
mcg - Microgram (top)
MD - Medical doctor (top)
Mg - Magnesium (top)
mg - milligram (top)
Medicaid - A partnership between the federal government
and individual states to share the cost of medical coverage for welfare
recipients and to allow states to provide the same coverage to low-income
workers not eligible for welfare. Programs vary greatly from state
to state. (top)
Medically Necessary - A specific healthcare service
or supply that your insurance company has determined is required
for your medical treatment and is also the most efficient and economical
way to provide that service. (top)
Medicare -
The federal government program that may provide hospital and medical
insurance through social security taxes to people age 65 and over,
those who have permanent kidney failure, and certain people with
disabilities. (top)
Medicare-Approved Facility -
A facility that meets Medicare standards for the number of transplants
they do and the quality of patient outcomes. (top)
Medigap Policy (MedSupp,
Medicare Supplementary) -
Private insurance that helps cover some of the gaps in Medicare coverage. (top)
MELD/PELD Score -
MELD - The Model for End-Stage Liver
Disease (MELD) is a numerical scale, ranging from 6 (less ill) to
40 (gravely ill), that is used for adult liver transplant candidates.
It gives each individual a 'score' (number) based on how urgently
he or she needs a liver transplant within the next three months.
The number is calculated by a formula using three routine lab test
results.
PELD - Candidates
under the age of 18 are placed in categories according to the Pediatric
End-Stage Liver Disease (PELD) scoring system. PELD replaced the previous
Status 2B or 3 for pediatric patients; Status 1 remains in place and
is not affected by PELD.
PELD is similar to MELD but uses some different criteria
to recognize the specific growth and development needs of children.
PELD scores may also range higher or lower than the range of MELD scores. (top)
MI - Myocardial infarction (heart attack) (top)
min - Minute (top)
Mortality - Death (mortality rate = death rate). (top)
MRI - Magnetic resonance imaging. A type of radiaology procedure. (top)
ms -
Morphine sulfate (top)
Multiple Listing - Being on the organ transplant waiting
list at more than one transplant center. (top)
Na - Sodium (top)
National Organ Transplant Act (NOTA) -
Passed by Congress in 1984, NOTA initiated the development of a national
system for organ sharing and a scientific registry to collect and report transplant
data. It also outlawed the sale of human organs. (top)
Nephrotoxicity - Kidney damage, usually as a result of
medications or other substances. (top)
Nephrologist - A medical doctor who specializes in the
diagnoses, treatment and management of kidney diseases. (top)
NG -Nasogastric (top)
NGT - Nasogastric tube (top)
Nonadherence/Noncompliance - Failure to follow instructions
for medical care after transplantation. This may include not taking
medications as prescribed, not obtaining labs as instructed or missing
clinic appointments and tests. Nonadherence is a significant post-transplant
issue that often results in rejection, infection, an ultimately loss
of the graft. (top)
Nonfunction - A condition in which a transplanted organ
fails to "wake up" (work) after being transplanted into a recipient. (top)
NPO - Nothing by mouth (no food or fluids) (top)
NSAID -
Nonsteroidal anti-inflammatory drug (top)
O2 - Oxygen (top)
OD - Doctor of optometry, right eye (top)
od - every day, daily (top)
OLT - Orthotopic Liver Transplant
Organ Procurement Organization Area -
Each OPO provides organ procurement services for transplant centers throughout
the United States. An OPO service area can include a portion of a city, a portion
of a state or an entire state. OPOs distribute organs according to established
allocation policy. (top)
OR - Operating Room (top)
Organ - A part of the body, made up of various types of tissues,
that performs a particular function. Transplantable organs are the
heart, liver, lungs, kidneys, pancreas and intestines. (top)
Organ Donation -
To give an organ, such as your kidney, to someone in need of that organ, or
to have your organs removed for transplantation after your death. (top)
Organ Preservation -
Donated organs require special methods of preservation to keep them viable between
removal and transplantation. Without preservation, the organs will deteriorate.
The length of time organs and tissues can be kept outside the body vary depending
on the organ, the preservation solution and the preservation method. Common preservation times vary from two to four hours
for lungs to 48 hours for kidneys. (top)
Organ Preservation Time
| Heart |
4-6 hours |
| Liver |
12-18 hours
|
| Kidney |
24-48 hours |
| Heart-Lung |
2-4 hours |
| Lung |
2-4 hours |
| Pancreas |
12-18 hours |
| |
|
Organ and Tissue Procurement - Recovery of organs and
tissues for transplantation. (top)
Organ
Procurement and Transplantation Network (OPTN) - In 1984,
Congress passed the National Organ Transplant Act that mandated the
establishment and operation of a national organ procurement and transplantation
network (the OPTN). It also called for the establishment of a scientific
registry of patients receiving organ transplants. The purpose of
the OPTN is to manage the nation's organ procurement, donation and
transplantation system and to increase the availability of and access
to donor organs for patients with end-stage organ failure. Members
of the OPTN include all U.S. transplant centers, organ procurement
organizations (OPOs), histocompatibility laboratories, voluntary
healthcare organizations, medical
and scientific organizations and members of the general public.
The United Network of Organ Sharing (UNOS) established the OPTN in 1986 under contract with the Health
Resources and Services Administration (HRSA) of the U.S. Department
of Health and Human Services (HHS) and has operated it continually
since that time under contracts with HRSA. (top)
Organ Procurement Organization
(OPO) - OPOs are responsible for the recovery,
preservation and transportation of organs for transplantation. As a
resource to their communities, OPOs educate the public about the critical
need for organ donation. Currently, there are 59 OPOs around the country
and all are United Network of Organ Sharing (UNOS) members. (top)
Organ Procurement or Organ
Recovery - The act of surgically
removing an organ from a donor for transplantation. (top)
OS - Left eye (top)
OSOTC
- Ohio Solid Organ Transplant Consortium - A group
of people from all Ohio hospitals that provide liver transplant as
a treatment for adults. They have agreed to share the precious resource
of donated livers across the state and to judge together which patients
are listed for transplant within the state. (top)
OS - Left eye (top)
OT - Occupational
therapy (top)
OTC - Over-the-counter (medications) (top)
OU - Each eye
(top)
Out-of-Pocket Expenses - The portion of health costs
that must be paid by the insured person per year, including deductibles,
co-payments and co-insurance. (top)
Outpatient Care (Ambulatory
Care) - Medical testing or
treatment done without an overnight hospital stay, performed in a hospital
setting or at a doctor's office. (top)
oz - ounce
(top)
>
PAC - OPTN Patient Affairs Committee
(top)
PAKTX - Pancreas after kidney transplant (top)
Pancreas - A long, irregularly shaped gland that lies behind the
stomach and secretes enzymes into the small intestines to aid in the
digestion of proteins, carbohydrates and fats. Islet cells within
the pancreas consist of four types. The alpha cells secrete glucagons,
which raise blood sugar levels. The beta cells secrete insulin, which
lowers blood sugar levels. If the beta cells fail, the individual becomes
diabetic and may need to take insulin. The pancreas and the islet cells
can be donated and transplanted. (top)
Panel Reactive Antibody (PRA) -
This is a blood test used to find out how a potential organ recipient
will react to a donor organ. A patient with a PRA of 80 percent will likely
reject 80 percent of donor kidneys. Patients with a high PRA have priority on
the waiting list. The more antibodies in the recipient's blood, the more likely
the recipient will react against the donor organ. For example, patients who
have received multiple blood transfusions are likely to have more antibodies
in their blood and a higher PRA. (top)
pc - after meals (top)
PCA - Patient controlled analgesia (top)
PharmD - Doctor of pharmacy (top)
Pneumocystis (PCP) - A bacterial infection of the lungs
that is more common in immunosuppressed patients. Transplant recipients
are usually prescribed an antibiotic (Bactrium®/Septra®) to prevent this
type of pneumonia. (top)
Platelet - A type of blood cell that is involved in the
clotting process. Platelets help stop bleeding at the site of the injury
by clumping and forming a clot. If the platelet count is low, there
is an increased risk of bleeding. (top)
po - Orally, by mouth (top)
Portal Hypertension -
This term describes increased pressure in the veins that collect blood
from the stomach, spleen, pancreas and intestines (the portal system).
The blood from all the veins of these organs is collected into the
portal vein, which drains into the liver. In a diseased liver that
has fibrosis or cirrhosis, the blood from the portal vein may not be
able to flow easily through the liver. Increased pressure then develops
in the portal vein and can cause an enlarged spleen, fluid in the abdomen
(ascites) and/or enlarged veins in the stomach or esophagus ( varices). (top)
Pool - A group of people or objects with a similar characteristic
or function. (top)
Portal Vein - The vein that collects blood from the stomach,
spleen, pancreas and intestines and carries that blood to the liver. (top)
Potassium - A mineral required for normal body functioning.
Potassium is important in helping the heart, nerves and muscles function
properly. Potassium also helps change carbohydrates into energy and
in forming proteins. The kidneys excrete any extra potassium in the
body. It is important to follow potassium levels after transplant because
some antirejection medications can cause an increase in the potassium
level. (top)
Potential Transplant Recipient - A transplant candidate
who has been ranked by the OPTN computer match program as the person
to whom an organ from a specific deceased organ donor is to be offered.(top)
Pre-authorization (Pre-certification) -
The process of notifying and getting approval from your insurance company
before you proceed with an elective (non-emergency) medical procedure.
If your insurance plan requires pre-certification and you do not obtain
it, your share of the cost will be higher.(top)
Pre-existing condition - Any disease, illness, sickness
or condition that was diagnosed or treated by a provider (insurance
company) in the 12 months before the start date of your insurance coverage;
also, anything that caused symptoms in those 12 months that would cause
you to seek medical care.(top)
Preferred Provider Organization
(PPO) - A group of hospitals
or physicians who have signed a contract with a particular insurance
company to provide care to their members, usually at a discount. If
you have a PPO insurance plan, your share of the cost is usually lower
if you use one of the designated providers.(top)
Premium - Amount paid to an insurance company for providing
medical or disability coverage under a contract.(top)
Private Health Plan - An insurance policy obtained by
an individual, not through an employer.(top)
prn - As needed; part-time. (top)
Procurement - The surgical procedure of removing a donated
organ or tissue.(top)
Prophylactic Antibiotics - Medications that are prescribed
to prevent certain infections in a specific group of patients who are
at a higher risk for these infections. (top)
Pruritis -
Itching - Patients with liver disease may have increased itching due
to liver dysfunction since there is an accumulation of bile salts in
their skin. (top)
PT - Physical therapy (top)
PTLD - Post-Transplant Lymphoproliferative Disease -
A wide spectrum of viral disorders associated with the Epstein Barr
Virus (EBV) that may range from a self-limiting mononucleosis ("mono",
glandular fever) to a type of lymphoma, or cancer of the lymph nodes.
PTLD is a complication of a suppressed immune system and occurs in
only a small percentage of patients. Treatment includes lowering immunosuppression
and administering antiviral medications. (top)
Pulmonary - Having to do with, or referring to, the lungs.(top)
q - every (top)
qd - every day (top)
qid - Four times per day (top)
qod - every other day (top)
R&B - (hospital) room and board (top)
RBC - Red blood cell (top)
Recipient -
The patient who receives the organ from the donor during an operation
(liver transplantation). (top)
Recovery or Retrieval - The surgical procedure of removing an
organ or tissue from a donor. (top)
Rejection -
Rejection occurs when the body tries to destroy a transplanted organ or tissue
because it is a foreign object. Immunosuppresive (anti-rejection) drugs help
prevent rejection. (top)
Renal - A term that refers to the kidney or having to do with
the kidney. (top)
Retransplantation - Due to organ rejection or transplant failure,
some patients need another transplant and return to the waiting list
to be retransplanted. (top)
Required Request - Hospitals must tell the families of suitable
donors that their loved one's organs and tissues can be used for transplant.
This law is intended to increase the number of donated organs and tissues
for transplantation by giving more people the opportunity to donate. (top)
Routine Referral -
Hospitals are required on or before each death to call the Organ Procurement Organization (OPO) in order to determine
suitability for organ, eye and tissue donation. The OPO, in consultation with
the patient's attending physician or his or her designee, will determine the
suitability for donation. (top)
RN - Registered nurse (top)
ROM - Range of motion (as in exercise) (top)
RPT - Registered physical therapist (top)
RR - Recovery Room (top)
RST - Registered speech therapist (top)
Rx - Prescription (top)
SC, sc - Subcutaneous (injection) (top)
Scientific Registry of Transplant
Recipients (SRTR) -
In 1987, Congress passed the National Organ Transplant Act that mandated the
establishment of the Organ Procurement and Transplantation Network
and SRTR. The purpose of the SRTR is to provide ongoing research to
evaluate information about donors, transplant candidates and recipients,
as well as patient and graft survival rates. The SRTR contains historical
data from October 1, 1987 to the present. The registry tracks all transplant
patients from the time of transplant through hospital discharge, and
then annually for up to 3 years or until graft failure or death. URREA,
University Renal Research and Education Association, operates the SRTR
under contract with the Federal Government. (top)
Second Opinion -
A medical opinion provided by a second physician or medical expert after one
physician has provided a diagnosis or recommended treatment to an individual. (top)
Sensitization -
Patients become sensitized when there are antibodies in the blood,
usually because of pregnancy, blood transfusions or previous rejection of an
organ transplant. Sensitization is measured by panel reactive antibody (PRA).
Highly sensitized patients are less likely to match with a suitable donor and
more likely to reject an organ than unsensitized patients. (top)
Sensitized - Having antibodies in the blood, which means a potential
recipient will react against a greater number of potential organs.
Sensitization usually occurs because of pregnancy, blood transfusions
or previous rejection of an organ transplant. Sensitization is measured
by panel reactive antibody (PRA). a highly sensitized patient is more
likely to react against an organ and, therefore, has a smaller pool
of potential organs that he/she may receive. (top)
Shingles -
A viral infection caused by the herpes zoster virus that usually affects an
area by a nerve, resulting in fluid-filled blisters and pain. Shingles are most
commonly seen on the neck, abdomen and legs. The virus can also affect the
nerves of the eye. (top)
Side Effect - An unintended reaction to a drug. (top)
Social Security Administration - A federal government program
best known for its retirement benefits. The Social Security Administration
also administers disability benefits. (top)
Sodium- A type of salt found in the blood and required by the
body to maintain the balance between electrolytes and water. (top)
soln - Solution (top)
Spend Down -
For disabled people who have higher incomes but cannot pay their medical bills.
Under this program, a person pays part of his or her monthly medical expenses
(the spend down), then Medicaid steps in and pays the rest. Eligibility is
determined on a case-by-case basis. (top)
SPKTX - Simultaneous pancreas and kidney transplant (top)
Spleen -
An organ located under the rib cage on the left side of the abdomen. The spleen
removes old or deformed red blood cells white blood cells, and platelets. It
also makes lymphocytes, a type of white blood cell that help produce antibodies.
The spleen may enlarge (splenomegaly) in patients with liver disease. (top)
Splenomegaly -
Splenomegaly is a term used to describe an enlarged spleen. In patients with
liver disease, splenomegaly results from portal hypertension. Splenomegaly can
cause a low platelet count that may increase the risk of bleeding. (top)
Split Liver - A liver obtained from a cadaveric donor which is
divided into two usable portions and then given to two different recipients. (top)
SSA - Social Security Administration (top)
SSDI - Social Security Disability Insurance (top)
SSI - Social Security Income (top)
ST - Speech therapy (top)
Status - A code used to indicate the degree of medical urgency
for patients awaiting heart or liver transplants. (top)
Steroids - Naturally occurring substances, such as hormones, found
in your body that help control important functions. Synthetic or manmade
steroids can be used to suppress your immune system. (top)
subcu, subq - Subcutaneous (injection) (top)
Supplemental Policy (Medigap Policy) -
An insurance policy offered by private insurance companies, not the government,
designed to pay for some of the costs that Medicare does not cover. These policies
have limited coverage for medicines. (top)
Survival
Rates - Survival rates indicate what percentage of patients
are alive or organs (grafts) are still functioning after a certain
amount of time. Survival rates are used in developing organ allocation
policy. Since survival rates improve with technological and scientific
advances, developing policies that reflect and respond to these advances
will also improve survival rates. (top)
SW - Social worker (top)
Sx - Symptoms (top)
syr - Syrup or syringe (top)
Systolic -
This is the "top number" of blood pressure measurement.
The systolic pressure measures the pressure as the heart muscle contracts
to pump blood around the body. (top)
Systolic Blood Pressure - The top number in your blood pressure
(the 120 in a blood pressure of 120/80). It measures the maximum pressure
exerted when the heart contracts. (top)
T Cells - T cells are a type of lymphocyte, or white blood cell,
that develop in the thymus gland which is located in the upper chest
in front of the heart. T cells are associated with acquired immunity,
or the ability of the body to fight an infection or foreign substance
that it was exposed to in the past. T cells play a major role in the
rejection process. (top)
T Tube -
A "T" shaped stent sometimes placed in the bile duct
after transplantation or other forms of surgery. The top of the "T"
keeps the junction of your bile duct to the new liver's bile duct open,
while the stem of the "T" exists through your skin and is kept under
a bandage during the limited time (several months) the tube is needed. (top)
Termination of Benefits - Health insurance benefits stop when
an individual has reached the lifetime maximum amount or when an individual
is no longer eligible for the plan due to nonpayment of premiums or
leaving his or her job. (top)
Thoracic - Referring to the heart, lungs or chest. (top)
Thrush - A fungal infection that looks like white plaques or spots
in the mouth (oral mucosa), throat and on the tongue. Patients who
are immunosuppressed are more at risk for developing thrush. (top)
tid - Three times per day (top)
Tissue - An organization of similar cells that perform a special
function. Examples of tissues that can be transplanted are blood, bones,
corneas, heart valves, ligaments, veins and tendons. (top)
Tissue
Typing - The examination of human leukocyte antigens (HLA)
in a patient, tissue typing (genetic matching), is done for all donors
and candidates in kidney transplantation to help match the donor to
the most suitable recipient. (top)
TPR - Temperature, pulse, and respiration (top)
Transplant, Transplantation -
To transfer a section of tissue or complete organ from its original position
to a new position, for example, to transfer a healthy organ from one person's
body to the body of a person in need of a new organ. (top)
Transplant Candidate - An individual who has been identified as
medically suited to benefit from an organ transplant and has been placed
on the waiting list by the transplant program. (top)
Transplant Physician -
A physician who provides nonsurgical care and treatment to transplant patients
before and after transplant. (top)
Transplant Program - A component within a transplant hospital
which provides transplantation of a particular type of organ. (top)
Transplant Recipient - A person who has received an organ transplant. (top)
Transplant Surgeon -
A surgeon who specializes in the transplantation of organs. Typically a general
surgeon who has training in liver, kidney and pancreas transplantation or a
cardiothoracic surgeon who has special training in heart or lung transplantation. (top)
TX - Transplantation (top)
Tx - Treatment (top)
u - unit (top)
U&C Fee - Usual and customary fee (top)
Ultrasound - A test that displays internal bodily organs, blood
vessels, and ducts using sound waves. An ultrasound of the liver may
be obtained to examine the size of the liver and spleen, the size and
blood flow in the hepatic artery and portal vein and the size and
patency of the bile ducts. (top)
UNOS - United Network for Organ Sharing -
A nationwide umbrella for the transplant community; a non-profit organization
that administers and maintains the Nation's organ transplant waiting
list under contract with the Health Resources and Services Administration
of the U.S. Department of Health and Human Services. Located in Richmond,
Virginia, UNOS also brings together medical professionals, transplant
recipients and donor families to develop organ transplantation policy. (top)
URI - Upper respiratory infection (top)
URREA -
University Renal Research and Education Association -
A non-profit organization established for the purpose of conducting
clinical and economic studies. It administers the Scientific Registry
of Transplant Recipients (SRTR) under contract with the Health Resources
and Services Administration of the U.S. Department of Health and Human
Services. Located in Ann Arbor, Michigan, URREA is made up of researchers,
biostatisticians, programmer analysts and research assistants who have
experience in studying health-related issues. (top)
U.S. Scientific Registry of Transplant
Recipients - A database
of post-transplant information. Follow-up data on every transplant
are used to track transplant center performance, transplant success
rates and medical issues impacting transplant recipients. (top)
Varices - Enlarged blood vessels, particularly in the stomach and
esophagus. (top)
Vascular - Referring to blood vessels and circulation. (top)
Ventilator - A machine that forces air into the patient's
respiratory system when the patient is not able to breathe properly. (top)
Virus - A group of tiny infectious organisms that can
only grow and reproduce themselves while living within cells of the
body. After reproduction, the new viruses look for new cells to enter. (top)
Vital Signs (VS) - The measurement of temperature, blood pressure,
heart rate and respiratory (breathing) rate. (top)
Waiting List - After evaluation by the transplant team a patient
is added to the national waiting list by the transplant center. Lists
are specific to organ type: heart, lung, kidney, liver, pancreas, intestine,
heart-lung and kidney-pancreas.
Each time a donor organ becomes available, the UNOS computer generates
a list of candidates based on factors that include genetic similarity,
organ size, medical urgency, proximity of the donor to potential recipients
and time on the waiting list. Through this process, a match run list
is generated each time an organ becomes available that best "matches"
possible patients to a donated organ. (top)
Waiting Period - A period of time when you are not covered by
insurance for a particular problem, such as a pre-existing condition. (top)
WBC - White blood cell (top)
Wean - To slowly withdraw or reduce; Immunosuppression, particularly
steroids, may be weaned slowly over time in patients who do not reject
the transplanted liver. (top)
White Blood Cell - This is a type of blood cell that fights infection. (top)
wk - week (top)
wt - weight (top)
yr - Year (top)
|